Navigating the Complex Landscape of Pulmonary Arterial Hypertension: A Roadmap for Pharmacists
ACPE Number:0204-0000-25-409-H01-P Content Release Date: February 19, 2026 Expiration Date: February 19, 2027 Activity Type: Application-based CE Credits: 1.5 contact hours (0.15 CEUs) Activity Fee: Free
Activity Overview
The last 30 years have seen significant advances in the diagnosis, treatment, and management of pulmonary arterial hypertension (PAH). Improvements in understanding the pathways underlying endothelial dysfunction and vascular arteriole remodeling involved in the pathogenesis of PAH, targeted therapies, and enhanced diagnostic and monitoring tools are reflected in new evidence-based guidelines. This educational activity will present the latest guidelines and recommended treatment options for PAH, including drug selection, combination therapies, and when and how to adjust and escalate treatment. This activity will also discuss drug therapy mechanisms of action, potential interactions, adverse effects, and considerations to support access and adherence.
*Please note, this activity was presented live on December 9, 2025 as part of the ASHP 2025 Midyear Clinical Meeting & Exhibition. You can only claim credit once for this activity; live or home study.
The American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education with Commendation.
This activity was planned to meet the educational needs of pharmacists who practice in hospitals, health systems, ambulatory clinics, and community settings who care for or are interested in the care of patients with pulmonary arterial hypertension.
Jared Frost, PharmD, BCCP, Activity Chair Clinical Pharmacy Specialist – Cardiology Cardiology Pharmacy Residency Director Advocate Health – Aurora St. Luke's Medical Center Milwaukee, Wisconsin
Jared Frost, PharmD, BCCP is a Clinical Pharmacy Specialist in cardiology and the PGY2 Cardiology Residency Program Director at Aurora St. Luke's Medical Center in Milwaukee, WI. Dr. Frost earned his Doctor of Pharmacy degree from Drake University and completed both PGY1 and PGY2 Cardiology Pharmacy Residencies at Aurora St. Luke's. In his current role he oversees medication practices across the cardiac catheterization and electrophysiology labs, cardiovascular surgery, and pulmonary hypertension services. Dr. Frost is an active member of the American College of Cardiology, the National Lipid Association, and the Pharmacy Society of Wisconsin.
Zachary Klick, PharmD, BCCP, BCPS, BCACP, CPP Cardiology Pharmacist Cardiology Pharmacy Residency Program Director Atrium Health Wake Forest Baptist Winston Salem, North Carolina
Zachary Klick, PharmD, BCPS, BCACP, BCCP, CPP, is a board-certified clinical pharmacist specializing in cardiology. He earned his PharmD from Duquesne University and completed his PGY1 at Carilion Clinic Roanoke Memorial Hospital, followed by a PGY2 in Cardiology at HCA/UTHSC. Dr. Klick has experience in both inpatient and outpatient cardiology, managing patients with advanced heart failure, pulmonary hypertension, and coronary artery disease.
Jeffery S. Vender, MD, MCCM, MBA is the Emeritus, Harris Family Foundation Chairman of the Department of Anesthesiology at NorthShore University Health System in Evanston, Illinois and a Clinical Professor at the University of Chicago Pritzker School Of Medicine in Chicago, Illinois. He is a past member of the NorthShore University Health System Faculty Practice Associates Board of Directors, Past Chair of the Medical Executive Committee for the Professional Staff at NorthShore and previously served on Northshore’s Board of Directors. Dr. Vender served as Chair of Anesthesia from 1990-2015 and received an appointment of adjunct Professor of Biomedical Engineering at Northwestern University. He served as the Director of the Critical Care Services at Evanston Hospital from 1987-2000 and the Interim Chairman at Northwestern University Department of Anesthesiology from July 1999 until October 2000. Dr. Vender has participated and Chaired numerous state and national committees of various medical organizations, edited several medical texts, has published over 135 articles and book chapters and has been an invited lecturer at over 250 national and international meetings on topics of anesthesiology, critical care, organizational change, and leadership. In addition, Dr. Vender serves as an editor and/or reviewer for many medical journals.
In accordance with our accreditor’s Standards of Integrity and Independence in Accredited Continuing Education, ASHP requires that all individuals in control of content disclose all financial relationships with ineligible companies. An individual has a relevant financial relationship if they have had a financial relationship with an ineligible company in any dollar amount in the past 24 months and the educational content that the individual controls is related to the business lines or products of the ineligible company.
An ineligible company is any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. The presence or absence of relevant financial relationships will be disclosed to the activity audience.
No one in control of the content of this activity has a relevant financial relationship (RFR) with an ineligible company.
To receive CE credit, complete the steps below within 60 days of completing the activity.
View the entire presentation and answer all polling questions.
Click "Complete Activity" on last slide then complete the evaluation to claim credit.
Verify credits were successfully transferred to CPE Monitor before the ACPE 60-day deadline by checking your NABP eProfile account.
Important Note – ACPE 60 Day Deadline Per ACPE requirements, CPE credit must be claimed within 60 days of being earned – no exceptions! To verify that you have completed the required steps and to ensure your credits have been reported to CPE Monitor, we encourage you to check your NABP eProfile account to validate your credits were transferred successfully before the ACPE 60-day deadline. After the 60 day deadline, ASHP will no longer be able to award credit for this activity.
