Finding Success in the Management of Carbapenem-Resistant Enterobacteriaceae: Defining the Role of Newer Agents

ACPE Activity Number: 0204-0000-18-002-H01-P
Activity Date: January 31, 2018
Expiration Date: January 31, 2021
Activity Type: Knowledge-based  
CE Credits: 1.0 hour, no partial credit
Activity Fee: Members – Free / Non-Member – Not Available

Accreditation for Pharmacists

The American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

This activity is a recording from a live webinar and those that claim credit for the live webinar should not claim credit for this activity.

Target Audience

This continuing pharmacy education activity is designed for pharmacists with an interest in infectious diseases.

Activity Overview

Carbapenem-Resistant Enterobacteriaceae (CRE) is an urgent threat to public health with mortality estimated at >30-50%. Until recently, polymyxin-based antibiotics were the only available options. However, integration of polymyxin-based regimens remains complicated due to suboptimal pharmacokinetics, adverse events, and variability in clinical response. Currently, there are several compounds with activity against CRE. The purpose of this presentation is to discuss clinical outcome data associated with these compounds and where they may fit in practice.

Learning Objectives

  • Describe the epidemiology of Carbapenem-Resistant Enterobacteriaceae.
  • Discuss clinical outcomes associated with the current management of Carbapenem-Resistant Enterobacteriaceae.
  • Discuss new antibiotics available for the treatment of Carbapenem-Resistant Enterobacteriaceae.
  • Identify opportunities to integrate the newer agents into clinical practice.

Schedule of Educational Activities

  • Discuss clinical data associated with CRE.
  • Discuss strategies for infectious disease care.

Faculty Information

  • Kenneth P. Klinker, Pharm.D., Clinical Associate Professor; Clinical Specialist, Infectious Diseases, University of Florida College of Pharmacy; UF Health Shands Hospital, Gainesville, Fla.
  • Christina DeRemer, Pharm.D., BCPS, FASHP, Clinical Associate Professor, Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Fla.


In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support and the Accreditation Council for Pharmacy Education’s Standards for Commercial Support, ASHP requires that all individuals involved in the development of activity content disclose their relevant financial relationships. A person has a relevant financial relationship if the individual of his or her spouse/partner has a financial relationship (e.g. employee, consultant, research grant recipient, speakers bureau, or stockholder) in any amount occurring the in the last 12 months with a commercial interest whose products or services may be discussed in the educational activity content over which the individual has control. The existence of these relationships is provided for the information of participants and should not be assumed to have an adverse impact on the content.

In keeping with this requirement, ASHP ask that all faculty, advisory board members, planning committee members, content development consultants, and staff complete a disclosure form for each program in which they are involved. Anyone who refuses to disclose relevant financial relationships must be disqualified from any involvement with a continuing pharmacy education activity.

  • Faculty, planner, ASHP Staff and consultants report no relevant financial relationships pertinent to this activity.

Methods and CE Requirements

This activity consists of recorded faculty slides presentations, active learning activities, discussion, and handouts. Participants must participate in the entire activity and complete all the required components to claim continuing pharmacy education credit online at ASHP eLearning Portal. Follow the prompts to claim and view or print the statement of credit immediately or within 60 days of completing the activity.

Per ACPE requirements, CPE credit must be claimed within 60 days of being earned.

System Technical Requirements

System Requirements Courses and learning activities are delivered via your Web browser and Acrobat PDF.  Users should have a basic comfort level using a computer and navigating web sites.

View the minimum technical and system requirements for learning activities.